Ovarian reserve of infertile women in Libreville: A retrospective analysis of 124 cases at the University Mother and Child Hospital in Libreville, Gabon

Opheelia Makoyo, Lionel W Moungala, Elysabeth Lendoye

Abstract

There has been an increasing number of sub-fertile women in Gabon during the last 20 years. Antral follicle count (AFC) and serum anti-Mullerian hormone (AMH) are known as the most accurate markers of ovarian reserve in women and are related to age and weight. Therefore, the current study examines the relationship between AFC and serum AMH with age and weight among sub fertile Gabonese women. This is a retrospective study carried out in the assisted reproduction department of the Mother and Child University Hospital of Libreville. Over a period of 2 years, from 1st June 2019 to 30th May 2021. From the patient records we collected the following data, age, weight CFA and AMH of 124 women who had consulted for infertility. We excluded incomplete files. The average age and weight of women participating in the current study were 38 (±5.74) years and 76.3 (±14.59) kg. The average serum AMH concentration was 2.33 (±2.17) ng/mL) while the average AFC was 14.63 (±11.37). Significant negative correlation between the age and the serum AMH (r2= -0.368; p<0.0001) and between the age and the CFA (r2=-0.560; p<0.0001) were observed in the current study. This study suggests that sub-infertile women residing in Gabon generally have normal serum AMH concentration and AFC levels. Age significantly impact serum AMH and AFC levels. (Afr J Reprod Health 2023; 27 [3]: 19-24).

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