Fructose Concentration in Seminal Fluids and the Deoxyribonucleic Acid Content of Spermatozoa from Infertile Human Males

I.A.O. Oforofuo, UE. Onakewhor, I. Enuman

Abstract

Seminal fructose concentration and deoxyribonucleic acid (DNA) content of spermatoza from a group of 35 infertile male patients were measured. While six patients were azoospermic, 29 (83%) had oligospermia whose seminal fluid analysis showed (1) higher fructose levels and (2) higher DNA content per spermatozoon compared with normospermic age-matched 24 male controls who were similarly investigated within the same period. There was no significant quantitative correlation between sperm density, plasma testosterone, and seminal fructose concentration among the normospermic and oligospermic subjects. The oligospermia was probably caused by spermatic arrest which could explain the higher spermatic DNA content in the oligospermic than in normospermic subjects. (AfrJReprod Health 1997;l(l):89—96)

KEY WORDS: Fructose, DNA, oligospermia, infertile, semen

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References

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