Prevalence of Asymptomatic Genital Infection among Pregnant Women in Benin City, Nigeria
Abstract
The prevalence of asymptomatic genital infection among pregnant women and their susceptibility to antibacterial agents was investigated to provide baseline data on common asymptomatic genital microorganisms and identify potentials for development of clinical disease among this cohort of patients. High vaginal swabs were obtained from five hundred consecutive and consenting pregnant women attending the antenatal clinic of the University of Benin Teaching Hospital (UBTH) and the Central Hospital, both in Benin City, Nigeria. A total of three hundred specimens showed significant microbial growth, giving a prevalence rate of 60% for asymptomatic genital infections. Candida albicans (65%), Staphylococcus aureus (51.8%) and Enterobacteriacae (E. coli and Klebsiellaspecies) were predominantly isolated, followed by Trichomonasvaginalis and Neisseria gonorrhoea. Most of the bacterial isolates were susceptible to ciprofloxacin, ceftazidime, cotrimoxazole, norfloxacin and augmentin. All the isolates except Streptococcus faecalis were resistant to ampicillin. These results show a high rate of asymptomatic genital tract infections among pregnant women in Benin City, which have implications for adverse maternal and neonatal outcomes. (Afr J Reprod Health 2002; 6[3]: 93–97)
Keywords: Genital infection, pregnant women, antibacterial agents, Nigeria.
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Brumfit W, Davies BJ and Rosser E. Urethral catheter as a cause of urinary tract infections in pregnancy and puerperium. Lancet 1961; 1: 1069.
Carey JC and Klebanoff MA. Bacterial vaginosis and other asymptomatic vaginal infections in pregnancy. Curr Women's Health Rep 2001; (1): 14–19.
Dalzell JE Jr and Lefevre ML. Urinary tract infections during pregnancy. Am Fam Physician 2000; 61(3): 713–721.
Williams JD, Leigh DA, Rosser ET and Brumfit W. The organisation and results of screening programmes for the detection of bacteriuria of pregnancy. J ObstetGynaecol Br Commonwealth 1965; 72(3): 327–335.
Coltman MD and Katherine D. Urinary tract infection — new thoughts on an old subject. The Practitioner 1979; 223: 351– 355.
Bello CS, Elegba OY and Dada JO. Sexually transmitted diseases in Northern Nigeria. Br J Ven Dis 1973; 59: 202–205.
Williams A. Textbook of Obstetrics and Gynaecology, Medical and Surgical Illness during Pregnancy and the Puerperium. Sixteenth Edition. 1980, 703.
Kass EH. Pyelonephritis, a major problem in preventive medicine. Ann Int Med 1965; 56: 46–53.
Rantz LA, Vosti SK and Monto AS. Host-parasite interaction in patient with infection due to Escherichia coli. J Lab Clin Med 1965; 66: 613–626.
EL-Kersh TA, Al-Nuaim LA, Kharfy TA, Al-Saleh SS and Al-Zamel FA. Detection of genital colonization of group B streptococci during late pregnancy. Saudi Med J 2002; 23(1): 56–61.
Gibbs RS. The relationship between infections and adverse pregnancy outcomes: an overview. Ann Periodontol 2001; 6(1): 153–163.
Locksmith G and Duff P. Infection, antibiotics and preterm delivery. SeminPerinatol 2001; 25(5): 295–309.
Donder GG, Verecken A, Bosmans E, Dekeersmaecker A, Salembier G and Spitz B. Definition of a type of abnormal vaginal flora that is distinct from bacterial vaginosis: aerobic vaginitis. Br J ObstetGynaecol 2002; 109(1): 34–43.
Cowan ST and Steel KJ. Manual for the Identification of Medical Bacteria. Second Edition. Cambridge: Cambridge University Press, 1974.
Bauer AW, Kirby WMM, Strerris JC and Turk M. Antibiotic susceptibility testing by a standardised single disc method. Amer J ClinPathol 1966; 45: 493.
Millar LK and Cox SM. Urinary tract infections complicating pregnancy. Infect Dis Clin North Am 1997; 11(1): 13–26.
Akerele J, Abhulimen P and Okonofua F. Prevalence of asymptomatic bacteriuria among pregnant women in Benin City, Nigeria. Br J ObstetGynaecol 2001; 21(2): 141–144.
Lewis J. Vaginal discharges. French Index of Differential Diagnosis. Eleventh Edition. Britain, 1979, 811–813.
Stanley G, Cloyton C, Lewis TL and Pinker CD. Vaginal discharges. In: Gynaecology by Ten Teachers. Fourteenth Edition. 1985, 102–108.
Turch M, Gofte BS and Peter Solor FRG. Bacteriuria in pregnancy: relationship to socio-economic factors. N Eng J Med 1962; 266: 857–866.
Peter A, Akah H, Hyacinth E and Onah P. Urinary tract infection in pregnancy in a Nigeria rural setting. W Afr J Pharmacol Drugs Res 1997; 113: 8–12.
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