Motivational Groups Support Adherence to Antiretroviral Therapy and use of Risk Reduction Behaviors in HIV Positive Nigerian Women: A Pilot Study
Abstract
Nigerian women comprise the fastest growing group of persons with AIDS in Africa. Antiretroviral therapy has transformed the course of HIV/AIDS to a treatable, chronic illness worldwide. The purpose of this pilot study was to assess the efficacy of a group intervention using motivational interviewing (MI) to promote adherence to antiretroviral therapy (ART) and use of risk reduction behaviors (RRB) among HIV-infected women in Nigeria. Recruited participants (n=60) were randomly assigned to the motivational group or the health promotion program (HPP) control group. The 6 month follow-up results indicate that, compared to the control group, MI participants reported significantly higher levels of adherence to ART, higher knowledge of HIV, higher use of condoms/protection during sexual encounters and decision-making not to have sex when no protection was available. The MI participants also had fewer mean number of sexual partners. MI in group format shows promise in promoting adherence to ART and use of RRB in HIV-infected Nigerian women. (Afr J Reprod Health 2012; 16[3]: 14-26).
Résumé
Les femmes nigérianes constituent le groupe de personnes atteintes du sida en Afrique qui s’élargit de manière de plus en plus rapide. La thérapie antirétrovirale a transformé le cours du VIH / SIDA à une maladie soignable et chronique dans le monde entier. Le but de cette étude pilote était d'évaluer l'efficacité d'une intervention de groupe en utilisant l'entrevue de motivation (IM) pour promouvoir l'adhésion à la thérapie antirétrovirale (TAR) et à l'utilisation des comportements de réduction des risques (CRR) parmi les femmes séropositives au Nigéria. Les participantes recrutées (n = 60) ont été assignées aléatoirement au groupe de motivation ou au groupe du programme témoin de la promotion de la santé (PPS). Les résultats complémentaires (n = 48) indiquent que par rapport au groupe témoin, les participantes de l’IM ont signalé les niveaux significativement plus élevés de l'adhésion à la TAR, un niveau plus élevé de connaissance du VIH, une plus grande utilisation du préservatif ou de protection lors de rapports sexuels et la prise de décision de ne pas avoir des rapports sexuels et la prise de décision de ne pas avoir des rapports sexuels quand il n’y a pas de protection. Les participantes de l’IM avaient également moins du nombre moyen de partenaires sexuels. L’IM en format de groupe est prometteur quand il s’agit de l’adhésion à la TAR et à l’utilisation de CRR chez les femmes nigérianes séropositives (Afr J Reprod Health 2012; 16[3]: 14-26).
Keywords: Adherence, Risk behaviors, Nigeria, HIV+ Women, Motivational interviewing
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United Nations. United Nations General Assembly Special Session Coutnry Report: Nigeria. UNGASS, 2010.
Federal Ministry of Health (FMOH). National HIV seroprevalence sentinel survey Technical report. Abuja, Nigeria, 2010:97.
Esu-Williams E, Mulanga-Kabeya C, Takena H, Zwandor A, Aminu K. Seroprevalence of HIV, HIV-2, and HIV-1 group O in Nigeria: Evidence of an increase of HIV infection. J. Acquir. Immune Defic. Syndr. 1997;16:204-10.
Imade G, Sagay A, Egah D, Onwuliri V, Grigg M, Egbodo C, et al. Prevalence of HIV and other sexually transmissible infections in relation to lemon or lime juice douching among female sex workers in Jos, Nigeria. Sex Health 2008;5(1):55-60.
The Population Council Inc. The experience of married adolescent girls in Northern Nigeria, 2007.
Smith DJ, Mbakwem, B.C. Life projects and therapeutic itineraries: marriage, fertility, and antiretroviral therapy in Nigeria. AIDS 2007;21(Supplement 5):S37-S41.
Smith DJ, Mbakwem BC. Antiretroviral therapy and reproductive life projects: mitigating the stigma of AIDS in Nigeria. Soc. Sci. Med. 2010;71(2):345-52.
Essien EJ, Ross MW, Ezedinachi EN, Meremikwu M. Cross-national HIV infection control practices and
fear of AIDS: a comparison between Nigeria and the USA. Int. J. STD AIDS 1997;8(12):764-71.
Aniekwu NI. Gender and human rights dimensions of HIV/AIDS in Nigeria. Afr. J. Reprod. Health 2002;6(3):30-7.
UNAIDS. Towards universal access to PMTCT, 2010.
AVERT Averting AIDS and HIV. HIV and AIDS in
Nigeria, 2011.
WorldHealthOrganization(WHO). The Treatment 2.0 Framework for Action: Catalysing the Next Phase of Treatment,Care and Support. Geneva,
Switzerland, 2011.
Mukhtar M, Adeleke S, Gwarzo D, Ladan ZF. Preliminary investigation of adherence to antiretroviral therapy among children in Aminu Kano Teaching Hospital, Nigeria. African Journal of AIDS Research 2006;5(2):141-44.
Nwauche CA, Erhabor, O., Ejele, O.A., Akani, C.I. . Adherence to antiretroviral therapy among HIVinfected subjects in a resource-limited setting in the Niger Delta of Nigeria. . African Journal of Health Sciences 2006;13(3-4):13-7.
Afolabi M, Ijadunola K, Fatusi A, Olasode O. Determinants of adherence to antiretroviral drugs among people living with HIV/AIDS in the Ife’Ijesa zone of Osun state, Nigeria. African Journal of Primary Health Care and Family Medicine
;1(1):1-6.
Erah PO, Arute JE. Adherence of HIV/AIDS patients to antiretroviral therapy in a tertiary health facility in Benin City. African Journal of Pharmacy and Pharmacology 2008;2(7):145-52.
Olowookere SA, Fatiregun AA, Akinyemi JO, Bamgboye AE, Osagbemi GK. Prevalence and determinants of nonadherence to highly active antiretroviral therapy among people living with HIV/AIDS in Ibadan, Nigeria. J Infect Dev Ctries 2008;2(5):369-72.
Shaahu VN, Lawoyin TO, Sangowawa AO. Adherence to highly active antiretroviral therapy (HAAT) at a Federal Medical Centre. Afr. J. Med. Med. Sci. 2008;37(1):29-36.
Salami A, Fadeyi A, Ogunmodede J, Desalu O. Factors influencing adherence to antiretroviral medication in Ilorin, Nigeria. Journal of the International Association of Physicians in AIDS Care
;9(3):191-5.
Taiwo BO, Idoko, J.A., Welty, L.J., Otoh, I., Job, G., Iyaji, P.G., Agbaji, O., Agaba, P.A., Murphy, R.L. Assessing the virologic and adherence benefits of patient-selected HIV treatment partners in a resource-limited setting. J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. 2010;54:85-92.
Abah IO, Falang, K., Finangwai, A., Iyaji, P., Wakdet, L., Odesanya, R., Job,G., Agbaji, O., Imade, G., Idoko, J.A., Kanki, P. Specific interventions to improve adherence to antiretroviral therapy in resource limited settings: the experience from Jos, Nigeria. 16th International Conference on AIDS. Toronto, Canada, 2006.
Ikechebelu J, Mbamara SU, Joe-Ikechebelu NN, Ezenwabachili AO. Sexual practices of people living with HIV in South Eastern Nigeria. Nigerian Journal of Clinical Practice 2009;12(4):416-20.
Obi SN, Onah HE, Ifebunandu NA, Onyebuchi AK. Sexual practices of HIV-positive individuals: The need for continued intervention in developing countries. J. Obstet. Gynaecol. 2009;29(4):329-32.
Ezeanochie M, Olagbuji B, Ande A, Oboro V. Fertility preferences, condom use, and concerns among HIVpositive women in serodiscordant relationships in the era of antiretroviral therapy. Int. J.Gynaecol. Obstet. 2009;107(2):97-8.
Akinyemi jO, Awolude, O.A., Adewole, I.F., Kanki, P.J. Condom use among antiretroviral therapy patients in Ibadan, Nigeria. Journal of Infection in Developing Countries 2010;4(8):495-502.
CDC. Effect of Antiretroviral Therapy on Risk of Sexual Transmission of HIV Infection and Superinfection. 2009.
Donnell D, Baeten, JD, Kiarie, J, Thomas, KK, Stevens, W, Cohen, CR, McIntyre, J, Lingappa, JR, Celum, C., . Heterosexual HIV-1 transmission after initiation of antiretroviral therapy: a prospective cohort analysis. Lancet 2010;375:2092-98.
Myron S. Cohen MD, Ying Q. Chen, Ph.D., Marybeth
McCauley, M.P.H., Theresa Gamble, Ph.D.,, Mina C. Hosseinipour MD, Nagalingeswaran
Kumarasamy, M.B., B.S., James G. Hakim, M.D.,, Johnstone Kumwenda FRCP, Beatriz Grinsztejn, M.D., Jose H.S. Pilotto, M.D., Sheela V. Godbole,
M.D.,, Sanjay Mehendale MD, Suwat
Chariyalertsak, M.D., Breno R. Santos, M.D., Kenneth H. Mayer, M.D.,, Irving F. Hoffman PA,
Susan H. Eshleman, M.D., Estelle PiwowarManning, M.T., Lei Wang, Ph.D.,, Joseph Makhema FRCP, Lisa A. Mills, M.D., Guy de Bruyn, M.B., B.Ch., Ian Sanne, M.B., B.Ch.,, et al. Prevention of HIV-1 infection with early antiretroviral therapy. The New England Journal of Medicine 2011;365(6):493-505.
Cohen MS, Chen YQ, McCauley M, Gamble T,
Hosseinipour MC, Kumarasamy N, et al. Prevention of HIV-1 Infection with Early Antiretroviral Therapy. N. Engl. J. Med. 2011;365(6):493-505.
Attia SE, Matthias. Muller, Monika. Zwahlen, Marcel. Low, Nicola. Sexual transmission of HIV according to viral load and antiretroviral therapy: systematic review and meta-analysis. AIDS 2009;23(11):1397404,.
Baeten JM, kahle, Erin, Lingappa< Jairam R., Coombs,
Robert W., Delany-Moretlwe, Sinead, NakkuJoloba, Edith, Mugo, Nelly R., Wald, A., Corey, Lawrence, Donnell, Deborah, Campbell, Mary S., Mullins, James I., Celum, Connie, for the Parners in Prevention HSV/HIV Transmission Study Team. Genital HIV-1 RNA Quantity Predicts risk of heterosexual HIV-1 Transmission. Sci Transl Med 2011;3(77).
Bennett JA, Young HM, Nail LM, Winters-Stone K, Hanson G. A telephone-only motivational intervention to increase physical activity in rural adults: a randomized controlled trial. Nurs Res 2008;57(1):24-32.
Resnicow K, Wallace DC, Jackson A, Digirolamo A, Odom E, Wang T, et al. Dietary change through African American churches: baseline results and program description of the eat for life trial. J Cancer Educ 2000;15(3):156-63.
Smith DE, Heckemeyer CM, Kratt PP, Mason DA. Motivational interviewing to improve adherence to a behavioral weight-control program for older obese women with NIDDM. A pilot study. Diabetes Care 1997;20(1):52-4.
Stein MD, Herman DS, Anderson BJ. A motivational intervention trial to reduce cocaine use. J Subst Abuse Treat 2009;36(1):118-25.
Parsons JT, Golub SA, Rosof E, Holder C. Motivational interviewing and cognitive-behavioral intervention to improve HIV medication adherence among hazardous drinkers: a randomized controlled trial. J Acquir Immune Defic Syndr 2007;46(4):443-50.
Velasquez MM, von Sternberg K, Johnson DH, Green C, Carbonari JP, Parsons JT. Reducing sexual risk behaviors and alcohol use among HIV-positive men who have sex with men: a randomized clinical trial. J Consult Clin Psychol 2009;77(4):657-67.
DiIorio C, McCarty F, Resnicow K, McDonnell Holstad M, Soet J, Yeager K, et al. Using motivational interviewing to promote adherence to antiretroviral medications: a randomized controlled study. AIDS Care 2008;20(3):273-83.
Golin CE, Earp J, Tien HC, Stewart P, Porter C, Howie L. A 2-arm, randomized, controlled trial of a motivational interviewing-based intervention to improve adherence to antiretroviral therapy (ART) among patients failing or initiating ART. J Acquir Immune Defic Syndr 2006;42(1):42-51.
Holstad MM, DiIorio, C., Kelley, M.E., Resnicow, K., Sharma, S. Group Motivational Interviewing to promote adherence to antiretroviral medications and risk reduction behaviors in HIV infected women. AIDS and Behavior 2010.
Fisher JD, Fisher WA, Cornman DH, Amico RK, Bryan A, Friedland GH. Clinician-delivered intervention during routine clinical care reduces unprotected sexual behavior among HIV-infected patients. J Acquir Immune Defic Syndr 2006;41(1):44-52.
Callahan EJ, Flynn NM, Kuenneth CA, Enders SR. Strategies to reduce HIV risk behavior in HIV primary care clinics: brief provider messages and specialist intervention. AIDS Behav 2007;11(5 Suppl):S48-57.
Golin CE, Patel S, Tiller K, Quinlivan EB, Grodensky CA, Boland M. Start Talking About Risks: development of a Motivational Interviewing-based
safer sex program for people living with HIV. AIDS Behav 2007;11(5 Suppl):S72-83.
Nollen C, Drainoni ML, Sharp V. Designing and delivering a prevention project within an HIV treatment setting: lessons learned from a specialist model. AIDS Behav 2007;11(5 Suppl):S84-94.
Rutledge SE. Single-session motivational enhancement counseling to support change toward reduction of HIV transmission by HIV positive persons. Arch Sex Behav 2007;36(2):313-9.
Dewing S, Mathews, C., Schaay, N., Cloete, A., simbayi, l., Chopra, M. The feasibility of implementing a sexual risk reduction intervention in routine clinical practice at an ARV clinic in Cape Town: A case study. AIDS Behavior 2010.
Evangeli m, Engelbrecht, s., Swartz, l., Turner, K., Forsberg, Soka, N. An evaluation of a brief motivational interviewing training course for HIV/AIDS counsellors in Western Cape Province, South Africa. AIDS Care 2009;21(2):189-96.
PASS 2008, NCSS, LLC, version 08.0.8 [program], 2008.
Holstad MM, DiIorio C, Magowe MK. Motivating HIV positive women to adhere to antiretroviral therapy and risk reduction behavior: the KHARMA Project. Online J Issues Nurs 2006;11(1):5.
Bandura A. The social foundation of thought and action: A social cognitive theory, 1986.
Holstad MM, Foster V, Diiorio C, McCarty F, Teplinskiy I. An examination of the psychometric properties of the Antiretroviral General Adherence Scale (AGAS) in two samples of HIV-infected individuals. J. Assoc. Nurses AIDS Care 2010;21(2):162-72.
Chesney MA, Ickovics JR, Chambers DB, Gifford AL, Neidig J, Zwickl B, et al. Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: the AACTG adherence instruments. Patient Care Committee & Adherence Working Group of the Outcomes Committee of the
Adult AIDS Clinical Trials Group (AACTG). AIDS Care 2000;12(3):255-66.
Carey MP, Schroder KE. Development and psychometric evaluation of the brief HIV Knowledge
Questionnaire. AIDS Educ. Prev. 2002;14(2):17282.
CDC. Core measures for HIV/STD risk behavior and prevention: Questionnaire-based measurement for surveys and other data systems. Sexual Behavior Questions Version 5.00. In: Group UCfDCHSBSW, editor, 2001.
UNICEF. At a glance: Nigeria, 2009.
Olley BO. The role of support group and duration of infection in HIV/AIDS patients' knowledge and attitudes to their illness. Afr. J. Med. Med. Sci.
;36:11-16.
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