Prevalence of asymptomatic bacteriuria among Thai diabetic pregnant women

Saifon Chawanpaiboon, Tirawan Buayaem, Supavadee Sodsee, Vitaya Titapant, Julaporn Pooliam

Abstract

Diabetic pregnant women are susceptible to urinary tract infection, which can result in preterm labor and a low birth weight of the neonate. This was a prospective observational study. In total, 110 diabetic pregnant women between 12–20 weeks of gestation were recruited. Asymptomatic bacteriuria (ASB) was diagnosed when the urinalysis presented a white blood cell (WBC) count ≥ 5 WBCs per high power field (HPF). Urine culture was later performed. Most of the diabetic pregnant women were classified as GDM A1. The prevalence of ASB was 7.2% (8/110 cases). Klebsiella aerogenes was found in only one case from urine culture. ASB was commonly found in the pregnant women with a high BMI, with statistical significance. The prevalence of ASB in the diabetic pregnant women was 7.2%. Urinalysis should be considered for diabetic pregnant women with a high body mass index. (Afr J Reprod Health 2021; 25[5]: 133-139).

Full Text:

PDF

References

Nicolle LE, Bradley S, Colgan R, Rice JC, Schaeffer A

and Hooton TM. Infectious Diseases Society of America guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults. Clin Infect Dis. 2005; 40(5): 643-54.

Lai YJ , Hsu TY, Lan KC, Lin H, Ou CY, Fu HC and Tsai

CC. Asymptomatic pyuria in pregnant women during the first trimester is associated with an increased risk of adverse obstetrical outcomes. Taiwan J Obstet Gynecol. 2017; 56(2): 192-5.

Celen S, Oruç AS, Karayalçin R, Saygan S, Unlü S, Polat

B and Danişman N. Asymptomatic bacteriuria and antibacterial susceptibility patterns in an obstetric population. ISRN Obstet Gynecol. 2011; 2011: 721-872.

Kacmaz B, Cakir O, Aksoy A and Biri A. Evaluation of

rapid urine screening tests to detect asymptomatic bacteriuria in pregnancy. Jpn J Infect Dis. 2006; 59(4): 261-3.

Smaill FM and Vazquez JC. Antibiotics for asymptomatic

bacteriuria in pregnancy. Cochrane Database Syst Rev. 2015(8): CD000490.

Srisompong J, Rahman S, Russameecharoen K, Tongsai

S, Seenama C and Koomanachai P. Prevalence and Accuracy of Screening Test of Asymptomatic Bacteriuria During Pregnancy in Siriraj Hospital. Open Forum Infectious Diseases. Fall 2017; 4: S348.

Renko M, Tapanainen P, Pokka T and Uhari M. Meta-

analysis of the significance of asymptomatic bacteriuria in diabetes. Diabetes Care. 2011;34(1):230-5.

Schneeberger C, Kazemier BM and Geerlings SE.

Asymptomatic bacteriuria and urinary tract infections in special patient groups: women with diabetes mellitus and pregnant women. Curr Opin Infect Dis. 2014 Feb;27(1):108-14. doi: 10.1097/QCO.0000000000000028. PMID: 24296584.

Jolley JA, Kim S and Wing DA. Acute pyelonephritis and

associated complications during pregnancy in 2006 in US hospitals. J Matern Fetal Neonatal Med 2012; 25:2494–2498.

Schneeberger C, Erwich JJHM, van den Heuvel ER, Mol

BWJ, Ott A and Geerlings SE. Asymptomatic bacteriuria and urinary tract infection in pregnant women with and without diabetes: Cohort study. Eur J Obstet Gynecol Reprod Biol. 2018; 222: 176-81.

Nicolle LE, Gupta K, Bradley SF, Colgan R, DeMuri

GP, Drekonja D, Eckert LO, Geerlings SE, Köves B, Hooton TM, Juthani-Mehta M, Knight SL, Saint S, Schaeffer AJ, Trautner B, Wullt B and Siemieniuk R. Clinical Practice Guideline for the Management of Asymptomatic Bacteriuria: 2019 Update by the Infectious Diseases Society of America. Clin Infect Dis. 2019; 68(10): e83-e110.

Sobel JD and Kaye D. Urinary tract infections. In:

Mandell GL, Bennett JE and Dolin R, editor. Principles and practice of infectious diseases. 1. Elsevier: Philadelphia 2010. p. 957-60.

Alvarez JR, Fechner AJ, Williams SF, Ganesh VL

and Apuzzio JJ. Asymptomatic bacteriuria in

pregestational diabetic pregnancies and the role of group B streptococcus. Am J Perinatol. 2010; 27(3): 231-4.

Smaill FM and Vazquez JC. Antibiotics for asymptomatic

bacteriuria in pregnancy. Cochrane Database Syst Rev. 2019; 2019(11).

Henderson JT, Webber EM and Bean SI. Screening for

Asymptomatic Bacteriuria in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA. 2019; 322(12): 1195-205.

Wilson ML and Gaido L. Laboratory diagnosis of urinary

tract infections in adult patients. Clin Infect Dis. 2004; 38(8): 1150-8.

Schwartz DS and Barone JE. Correlation of urinalysis and

dipstick results with catheter-associated urinary tract infections in surgical ICU patients. Intensive Care Med. 2006; 32(11): 1797-801.

Memişoğulları R, Yüksel H, Yıldırım HA and Yavuz O.

Performance Characteristics of Dipstick and Microscopic Urinalysis for Diagnosis of Urinary Tract Infection. Eur J Gen Med. 2010; 7(2): 174-8.

Refbacks

  • There are currently no refbacks.