Nutritional Factors Related to Male Fertility: Turkish Sample

Teslime Ö Yörüsün, Yasemin Akdevelioğlu, Recep O Karabacak, Nuray Bozkurt, Nevin Şanlıer, Süleyman Yeşil, Seyhan Gümüşlü


This study aimed to investigate the difference between infertile men and healthy (normozoospermic) men in terms of demographic characteristics, dietary habits, anthropometric measurements, and body composition. We included 80 males (40 subfertile and 40 healthy normozoospermic) between the ages of 25 and 54 years. Information was obtained from the participants regarding their socio-demographic characteristics, health status, dietary habits, and food intake. Food frequency questionnaires, food records, anthropometric measurements, body composition, and sperm analysis were statistically evaluated using IBM SPSS Statistics 20 programme. The findings of this study showed that the mean BMI of the subfertile group was significantly higher than that of the normozoospermic group. The frequency of eating out was significantly higher in the subfertile group than in the normozoospermic group. It was also determined that the consumption of fish was significantly lower; in contrast, consumption of sugar sweetened beverages, and alcohol was significantly higher in the subfertile group than in the normozoospermic group. Moreover, it was found that sugar sweetened bevareges, red meat, organ meats consumption are negatively; and that fish, egg, nut consumption are positively correlated with sperm parameters. In summary, in men receiving infertility treatment, excessive consumption of meat and sugary drinks should be considered cautiously. However, fish, nuts and eggs consumption should be provided in line with the nutrition guidelines. (Afr J Reprod Health 2020; 24[2]: 85-95).

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Dohle GR, Colpi GM, Hargreave TB, Papp GK,

Jungwirth A and Weidner W. EAU guidelines on male infertility. Eur Urol. 2005;48(5):703–11.

Fenkçi İV. Üreme Sağlığı ve Üremeye Yardımcı

Tedaviler. İstanbul: İstanbul Tıp; 2012.

Vayena E, Rowe PJ and Griffin PD. Current practices

and controversies in assisted reproduction: report of a meeting on medical, ethical and social aspects of assisted reproduction, held at WHO Headquarters in Geneva, Switzerland. 2002

Centers for Disease Control and Prevention. İnfertility

FastStats [Internet]. 2016 [cited 2019 Jul 16]. Available from:

Satar DA and Gençdal S. Sperm değerlendirmesi. Arşiv

Kaynak Tarama Derg. 2013;22(4).

Agarwal A, Mulgund A, Hamada A and Chyatte MR. A

unique view on male infertility around the globe. Reprod Biol Endocrinol. 2015;13(1):37.

Jørgensen N, Joensen UN, Jensen TK, Jensen MB,

Almstrup K, Olesen IA, Juul A, Andersen AM, Carlsen E, Petersen H, Toppari J and Skakkebek NE. Human semen quality in the new millennium: a prospective cross-sectional population-based study of 4867 men. BMJ Open. 2012;2(4):e000990.

Andersson A, Jørgensen N, Main KM, Toppari J, Meyts

ER, Leffers H, Juul A, Jensen TK and Skakkebek NE. Adverse trends in male reproductive health: we may have reached a crucial ‘tipping point.’ Int J Androl. 2008;31(2):74–80.

Carlsen E, Giwercman A, Keiding N and Skakkebæk

NE. Evidence for decreasing quality of semen during past 50 years. Bmj. 1992;305(6854):609–13.

Swan SH, Elkin EP and Fenster L. The question of

declining sperm density revisited: an analysis of 101 studies published 1934-1996. Environ Health Perspect. 2000;108(10):961.

Ramalingam M, Kini S and Mahmood T. Male fertility

and infertility. Obstet Gynaecol Reprod Med. 2014;24(11):326–32.

Attaman JA, Toth TL, Furtado J, Campos H, Hauser R

and Chavarro JE. Dietary fat and semen quality among men attending a fertility clinic. Hum Reprod. 2012;27(5):1466–74.

Wong WY, Thomas CMG, Merkus JMWM, Zielhuis GA

and Steegers-Theunissen RPM. Male factor subfertility: possible causes and the impact of nutritional factors. Fertil Steril. 2000;73(3):435–42.

Afeiche MC, Williams PL, Gaskins AJ, Mendiola J,

Jørgensen N, Swan SH and Chavarro JE. Meat intake and reproductive parameters among young men. Epidemiology. 2014;25(3):323.

Afeiche MC, Gaskins AJ, Williams PL, Toth TL, Wright

DL, Tanrikut C, Hauser R and Chavarro JE. Processed Meat Intake Is Unfavorably and Fish Intake Favorably Associated with Semen Quality Indicators among Men Attending a Fertility Clinic–3. J Nutr. 2014;144(7):1091–8.

Braga DP de AF, Halpern G, Rita de Cássia SF, Setti AS,

Iaconelli Jr A and Borges Jr E. Food intake and social habits in male patients and its relationship to intracytoplasmic sperm injection outcomes. Fertil Steril. 2012;97(1):53–9.

Afeiche M, Williams PL, Mendiola J, Gaskins AJ,

Jørgensen N, Swan SH and Chavarro JE. Dairy food intake in relation to semen quality and reproductive hormone levels among physically active young men. Hum Reprod. 2013;28(8):2265–75.

Mendiola J, Torres-Cantero AM, Moreno-Grau JM, Ten

J, Roca M, Moreno-Grau S and Bernabeu R. Food intake and its relationship with semen quality: a case-control study. Fertil Steril. 2009;91(3):812–8.

Eslamian G, Amirjannati N, Rashidkhani B, Sadeghi M-

R and Hekmatdoost A. Intake of food groups and idiopathic asthenozoospermia: a case–control study. Hum Reprod. 2012;27(11):3328–36.

Liu C-Y, Chou Y-C, Chao JC-J, Hsu C-Y, Cha T-L and

Tsao C-W. The association between dietary patterns and semen quality in a general Asian population of 7282 males. PLoS One. 2015;10(7):e0134224.

Gaskins AJ, Colaci DS, Mendiola J, Swan SH and

Chavarro JE. Dietary patterns and semen quality in young men. Hum Reprod. 2012;27(10):2899–907.

Afeiche MC, Bridges ND, Williams PL, Gaskins AJ,

Tanrikut C, Petrozza JC, Hauser R and Chavarro JE. Dairy intake and semen quality among men attending a fertility clinic. Fertil Steril. 2014;101(5):1280–7.

Hammoud AO, Wilde N, Gibson M, Parks A, Carrell DT

and Meikle AW. Male obesity and alteration in sperm parameters. Fertil Steril. 2008;90(6):2222–5.

World Health Organization. WHO laboratory manual for

the examination and processing of human semen. 2010

Merdol Kutluay T. Toplu Beslenme Yapılan Kurumlar

için Standart Yemek Tarifeleri. Ankara: Hatiboğlu Yayınevi. 2003

Baysal A. Türk mutfağından örnekler. Vol. 56. Kültür

Bakanlığı; 1993.

Lohman TG, Roche AF and Martorell R. Anthropometric

standardization reference manual. Vol. 177. Human kinetics books Champaign; 1988.

World Health Organization. Body mass index - BMI.

Kalaycı Ş. SPSS uygulamalı çok değişkenli istatistik

teknikleri. Vol. 5. Asil Yayın Dağıtım Ankara, Turkey; 2010.

Eliasson R. Semen analysis with regard to sperm

number, sperm morphology and functional aspects. Asian J Androl. 2010;12(1):26.

Bujan L, Mansat A, Pontonnier F and Mieusset R. Time

series analysis of sperm concentration in fertile men in Toulouse, France between 1977 and 1992. Bmj. 1996;312(7029):471–2.

Martini AC, Tissera A, Estofán D, Molina RI, Mangeaud

A, de Cuneo MF and Ruiz RD. Overweight and seminal quality: a study of 794 patients. Fertil Steril. 2010;94(5):1739–43.

Sermondade N, Faure C, Fezeu L, Shayeb AG, Bonde

JP, Jensen TK, Van Wely M, Cao J, Martini AC, Eskandar M, Chavarro JE, Koloszar S, Twigt JM, Ramlau-Hansen CH, Borges E Jr, Lotti F, Steegers-Theunissen RP, Zorn B, Polotsky AJ, La Vignera S, Eskenazi B, Tremellen K, Magnusdottir EV, Fejes I, Hercberg S, Lévy R and Czernichow S . BMI in relation to sperm count: an updated systematic review and collaborative meta-analysis. Hum Reprod Update. 2012;19(3):221–31.

Oostingh EC, Steegers-Theunissen RPM, de Vries JHM,

Laven JSE and Koster MPH. Strong adherence to a healthy dietary pattern is associated with better semen quality, especially in men with poor semen quality. Fertil Steril. 2017;107(4):916–23.

Demirci N. Erkek Fertilitesi ve Riskli Yaşam Biçimi

Davranışları. Florence Nightingale Hemşirelik Derg. 2014;22(1):39–45.

Dawson EB, Harris WA and Powell LC. Relationship

between ascorbic acid and male fertility. In: Aspects of Some Vitamins, Minerals and Enzymes in Health and Disease. Karger Publishers; 1990. p. 1–26.

Colagar AH and Marzony ET. Ascorbic acid in human

seminal plasma: determination and its relationship to sperm quality. J Clin Biochem Nutr. 2009;45(2):144–9.

Ebisch IMW, Pierik FH, De Jong FH, Thomas CMG and

Steegers-Theunissen RP. Does folic acid and zinc sulphate intervention affect endocrine parameters and sperm characteristics in men? Int J Androl. 2006;29(2):339–45.

Maersk M, Belza A, Stødkilde-Jørgensen H, Ringgaard

S, Chabanova E, Thomsen H, Pedersen SB, Astrup A and Richelsen B. Sucrose-sweetened beverages increase fat storage in the liver, muscle, and visceral fat depot: a 6-mo randomized intervention study. Am J Clin Nutr. 2011;95(2):283–9.

Emanuele MA and Emanuele NV. Alcohol’s effects on

male reproduction. Alcohol Health Res World. 1998;22:195–201.

Zhu Q, Van Thiel DH and Gavaler JS. Effects of ethanol

on rat Sertoli cell function: studies in vitro and in vivo. Alcohol Clin Exp Res. 1997;21(8):1409–17.

Anderson Jr RA, Berryman SH, Phillips JF, Feathergill

KA, Zaneveld LJD and Russell LD. Biochemical and structural evidence for ethanol-induced impairment of testicular development: apparent lack of Leydig cell involvement. Toxicol Appl Pharmacol. 1989;100(1):62–85.

Martin-Boyce A, David G and Schwartz D.

Genitourinary infection, smoking and alcohol in the male (author’s transl). Rev Epidemiol Sante Publique. 1977;25(3):209–16.

Williams P. Nutritional composition of red meat. Nutr

Diet. 2007;64:S113–9.

Gulaya NM, Margitich VM, Govseeva NM,

Klimashevsky VM, Gorpynchenko II and Boyko MI. Phospholipid composition of human sperm and seminal plasma in relation to sperm fertility. Arch Androl. 2001;46(3):169–75.

Zalata AA, Christophe AB, Depuydt CE, Schoonjans F

and Comhaire FH. The fatty acid composition of phospholipids of spermatozoa from infertile patients. Mol Hum Reprod. 1998;4(2):111–8.

Zararsiz I, Kus I, Davarci M, Kus MA, Kaman D and

Sarsilmaz M. Omega-3 yag asitlerinin siçan testis dokusu üzerine koruyucu etkileri/The protective effects of omega-3 fatty acids on rat testicular tissue. Dicle Tip Derg. 2011;38(4):382.

Safarinejad MR. Effect of omega‐3 polyunsaturated fatty

acid supplementation on semen profile and enzymatic anti‐oxidant capacity of seminal plasma in infertile men with idiopathic oligoasthenoteratospermia: a double‐blind, placebo‐controlled, randomised study. Andrologia. 2011;43(1):38–47.

Robbins WA, Xun L, FitzGerald LZ, Esguerra S,

Henning SM and Carpenter CL. Walnuts improve semen quality in men consuming a Western-style diet: randomized control dietary intervention trial. Biol Reprod. 2012; 87(4), 101-1.

Foulkes JA. The separation of lipoproteins from egg yolk

and their effect on the motility and integrity of bovine spermatozoa. Reproduction. 1977;49(2):277–84.

Shannon P, Curson B, Pitt CJ, Lai KC and Baas JW.

Effects of various fractions of egg yolk, BSA, and ovalbumin on sperm motility, and effect of storage on restoration of motility. New Zeal J Agric Res. 1983;26(3):297–302.

Miranda JM, Anton X, Redondo-Valbuena C, Roca-

Saavedra P, Rodriguez JA, Lamas A, Franco CM and Cepeda A. Egg and egg-derived foods: Effects on human health and use as functional foods. Nutrients. 2015;7(1):706–29.


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